PHARM ANALYSIS
Year : 2010  |  Volume : 2  |  Issue : 4  |  Page : 420-423

Zero order spectrophotometric method for estimation of escitalopram oxalate in tablet formulations


1 Faculty of Pharmaceutical Sciences, Jodhpur National University, Jodhpur - 342 008, India
2 Rajasthan Drug and Pharmaceutical Ltd, V.K.I. A. Road no. 12, Jaipur - 302 013, India

Correspondence Address:
S Sharma
Faculty of Pharmaceutical Sciences, Jodhpur National University, Jodhpur - 342 008
India
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DOI: 10.4103/0975-1483.71626

PMID: 21264107

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A new, simple, fast and reliable zero order spectrophotometric method has been developed for determination of Escitalopram Oxalate in bulk and tablet dosage forms. The quantitative determination of drug was carried out using the zero order values (absorbance) measured at 238 nm. Calibration graph constructed at 238 nm was linear in concentration range of 2-20 μg/ml with correlation coefficient 0.9999. The method was found to be precise, accurate, specific, and validated as per ICH guidelines and can be used for determination of Escitalopram Oxalate in tablet formulations.


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