Year : 2009  |  Volume : 1  |  Issue : 2  |  Page : 110-115

Skin penetration enhancement techniques

Department of Pharmaceutics, B.N. College of Pharmacy, Udaipur, India

Correspondence Address:
M Bharkatiya
Department of Pharmaceutics, B.N. College of Pharmacy, Udaipur
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DOI: 10.4103/0975-1483.55741

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Transdermal drug delivery systems allow delivery of a drug into the systemic circulation via permeation through skin layers at a controlled rate. In addition to the currently marketed formulations, new drugs are being formulated using the transdermal system because of the inherent advantage of administration by this route. It offers a noninvasive route of drug administration, although its applications are limited by low skin permeability. Innovative research exploiting penetration-enhancing strategies, such as iontophoresis, electroporation, microneedles, and sonophoresis, holds promise for the successful use of these drugs as consumer-friendly, transdermal dosage forms in clinical practice. This review outlines promising new technologies involved in enhancing transdermal permeation.

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